Canadian Medical Guide > Analytical, Diagnostic and Therapeutic Techniques and Equipment > Diagnosis > Diagnostic Techniques and Procedures > Diagnostic Techniques, Radioisotope Terms and Definitions

Diagnostic Techniques, Radioisotope

Medical Definition:	Any diagnostic evaluation using radioactive (unstable) isotopes. This diagnosis includes many nuclear medicine procedures as well as radioimmunoassay tests.
Guide Notes:	GEN only: prefer /radionuclide with dis; DF: DIAG TECHNIQUES RADIOISOTOPE

Diagnostic Techniques, Radioisotope Categories.

	Radioimmunoassay - Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.
	Radioisotope Dilution Technique - Method for assessing flow through a system by injection of a known quantity of radionuclide into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)
	Schilling Test - A diagnostic test in which vitamin B12 is tagged with radioactive cobalt, taken orally, and gastrointestinal absorption is determined via measurement of the amount of radioactivity in a 24-hour urine collection.

Diagnostic Techniques, Radioisotope Medical Definitions and Terms

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