Canadian Medical Guide > Organisms > Viruses > Defective Viruses > Sarcoma Viruses, Murine Terms and Definitions

Sarcoma Viruses, Murine

Medical Definition:	A group of replication-defective viruses, in the genus GAMMARETROVIRUS, which are capable of transforming cells, but which replicate and produce tumors only in the presence of Murine leukemia viruses (LEUKEMIA VIRUS, MURINE).
Guide Notes:	infection: coord IM with RETROVIRIDAE INFECTIONS (IM) + TUMOR VIRUS INFECTIONS (IM) + SARCOMA, EXPERIMENTAL (IM)
Previously Indexed:	Mouse Tumor Viruses (1966-1974)

Sarcoma Viruses, Murine Categories.

	Harvey murine sarcoma virus - A replication-defective mouse sarcoma virus (SARCOMA VIRUSES, MURINE) first described by J.J. Harvey in 1964.
	Kirsten murine sarcoma virus - A replication-defective murine sarcoma virus (SARCOMA VIRUSES, MURINE) capable of transforming mouse lymphoid cells and producing erythroid leukemia after superinfection with murine leukemia viruses (LEUKEMIA VIRUS, MURINE). It has also been found to transform cultured human fibroblasts, rat liver epithelial cells, and rat adrenocortical cells.
	Moloney murine sarcoma virus - A replication-defective murine sarcoma virus (SARCOMA VIRUSES, MURINE) isolated from a rhabdomyosarcoma by Moloney in 1966.

Sarcoma Viruses, Murine Medical Definitions and Terms

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