Canadian Medical Guide > Diseases > Hemic and Lymphatic Diseases > Hematologic Diseases > Blood Coagulation Disorders > Coagulation Protein Disorders > Activated Protein C Resistance Terms and Definitions




Activated Protein C Resistance

Medical Definition: A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.
Previously Indexed: Factor V/genetics (1994-1998),Protein C (1993-1998)

Activated Protein C Resistance Medical Definitions and Terms

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