| Medical Definition: |
A technique with which an unknown region of a chromosome can be explored. It is generally used to isolate a locus of interest for which no probe is available but that is known to be linked to a gene which has been identified and cloned. A fragment containing a known gene is selected and used as a probe to identify other overlapping fragments which contain the same gene. The nucleotide sequences of these fragments can then be characterized. This process continues for the length of the chromosome. |
| Guide Notes: |
technique for exploring an unknown region of a CHROMOSOME |
| Previously Indexed: |
Chromosome Mapping (1983-1990),Cloning, Molecular (1983-1990) |
CANADIAN
MEDICAL GUIDE