Canadian Medical Guide > Biological Sciences > Biological Phenomena, Cell Phenomena, and Immunity > Cell Physiology > Cell Cycle > Interphase Terms and Definitions
Interphase
Medical Definition: | The interval between two successive cell divisions during which the chromosomes are not individually distinguishable and DNA replication occurs. |
Guide Notes: | specific phases are available; NIM specific cell when merely test cell; coord with specific cell /cytol; permitted with micro-organisms |
Also Called: | G Phases |
Previously Indexed: | Cell Division (1966-1977),Mitosis (1968-1977) |
G0 Phase - Phase of the cell cycle where cells exist in a quiescent state. These cells have unduplicated DNA, degraded RNA and protein, and low enzyme activity. The ability to switch between G0 and G1 (and vice versa) determines the post-embryonic cell proliferation rate and is defectively controlled in neoplastic cells. | |
G1 Phase - Phase of the cell cycle preceding protein systhesis. The subphases of G1 include competence, entry (G1a), progression (G1b), and assembly (G1c), based on the effects of limiting growth factors, nutrients, or inhibitors. | |
G2 Phase - Phase of the cell cycle following DNA synthesis and preceding mitosis. The chromosomes are tetraploid in this phase. | |
S Phase - Phase of the CELL CYCLE following G1 and preceding G2 when the entire DNA content of the nucleus is replicated. It is achieved by bidirectional replication at multiple sites along each chromosome. |
Interphase Medical Definitions and Terms
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