Canadian Medical Guide > Chemicals and Drugs > Polycyclic Hydrocarbons > Steroids > Cardanolides > Cardiac Glycosides Terms and Definitions




Cardiac Glycosides

Medical Definition: Substances obtained from species of Digitalis, Strophanthus, and other plants that contain specific steroid glycosides or their semisynthetic derivatives and used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the Na(+)-K(+)-exchanging ATPase and they are often used in cell biological studies for that purpose.
Guide Notes: cardiotonics
Cardiac Glycosides Categories.
Canadian Medical Guide Definition Digitalis Glycosides - Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.

Cardiac Glycosides Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

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