Canadian Medical Guide > Diseases > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Glandular and Epithelial > Carcinoma > Carcinoma in Situ Terms and Definitions




Carcinoma in Situ

Medical Definition: A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.
Guide Notes: coord IM with precoord organ/neopl term (IM)
Also Called: Neoplasms, Intraepithelial
Previously Indexed: Carcinoma (1966-1972)
Carcinoma in Situ Categories.
Canadian Medical Guide Definition Cervical Intraepithelial Neoplasia - A malignancy arising in uterine cervical epithelium and confined thereto, representing a continuum of histological changes ranging from well-differentiated CIN 1 (formerly, mild dysplasia) to severe dysplasia/carcinoma in situ, CIN 3. The lesion arises at the squamocolumnar cell junction at the transformation zone of the endocervical canal, with a variable tendency to develop invasive epidermoid carcinoma, a tendency that is enhanced by concomitant human papillomaviral infection. (Segen, Dictionary of Modern Medicine, 1992)
Canadian Medical Guide Definition Prostatic Intraepithelial Neoplasia - A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.

Carcinoma in Situ Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

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