Canadian Medical Guide > Diseases > Hemic and Lymphatic Diseases > Hematologic Diseases > Bone Marrow Diseases > Myeloproliferative Disorders Terms and Definitions
Myeloproliferative Disorders
Medical Definition: | Disorders in which one or more stimuli cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. |
Guide Notes: | myelo- here = bone marrow, not spinal cord; GEN; prefer specifics |
Leukemoid Reaction - A peripheral blood picture resembling that of leukemia or indistinguishable from it on the basis of morphologic appearance alone. (Dorland, 27th ed) | |
Myelofibrosis - Replacement of the bone marrow by fibrous tissue, occurring in association with a myeloproliferative disorder or secondary to another, unrelated condition. (Dorland, 27th ed) | |
Myeloid Metaplasia - The occurrence of myeloid tissue in extramedullary sites. Specifically it is a syndrome characterized by splenomegaly, anemia, the presence of nucleated erythrocytes and immature granulocytes in the circulating blood, and extramedullary hemoatopoiesis in the liver and spleen. The primary form is also known as agnogenic myeloid metaplasia, myelosclerosis, and myelofibrosis. The secondary or symptomatic form may be associated with various diseases, including carcinomatosis, tuberculosis, leukemia, and polycythemia vera. (Dorland, 27th ed) | |
Polycythemia Vera - A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs. |
Myeloproliferative Disorders Medical Definitions and Terms
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