Canadian Medical Guide > Diseases > Hemic and Lymphatic Diseases > Hematologic Diseases > Blood Coagulation Disorders > Blood Coagulation Disorders, Inherited Terms and Definitions

Blood Coagulation Disorders, Inherited

Medical Definition:	Hemorrhagic and thrombotic disorders that occur as a consequence of inherited abnormalities in blood coagulation.
Previously Indexed:	Blood Coagulation Disorders (1995-2001)

Blood Coagulation Disorders, Inherited Categories.

	Antithrombin III Deficiency - An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis.
	Bernard-Soulier Syndrome - A familial coagulation disorder characterized by a prolonged bleeding time, unusually large platelets, and impaired prothrombin consumption.
	Protein C Deficiency - An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or premature thrombosis. (Stedman's Med. Dict., 26th ed.)
	Thrombasthenia - A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).
	Wiskott-Aldrich Syndrome - A rare, X-linked immunodeficiency syndrome characterized by eczema, thrombocytopenic purpura, and recurrent pyogenic infection. It is seen exclusively in young boys. Typically, IMMUNOGLOBULIN M levels are low and IMMUNOGLOBULIN A and IMMUNOGLOBULIN E levels are elevated. Lymphoreticular malignancies are common.

Blood Coagulation Disorders, Inherited Medical Definitions and Terms

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