Canadian Medical Guide > Biological Sciences > Biochemical Phenomena, Metabolism, and Nutrition > Biochemical Phenomena > Structure-Activity Relationship Terms and Definitions




Structure-Activity Relationship

Medical Definition: The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Other factors contributing to structure-activity relationship include chemical reactivity, electronic effects, resonance, and inductive effects.
Guide Notes: NIM with specific drug IM; no qualif; DF: STRUCT ACTIV RELAT
Structure-Activity Relationship Categories.
Canadian Medical Guide Definition Quantitative Structure-Activity Relationship - A quantitative prediction of the biological, ecotoxicological or pharmaceutical activity of a molecule. It is based upon structure and activity information gathered from a series of similar compounds.

Structure-Activity Relationship Medical Definitions and Terms

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