Canadian Medical Guide > Biological Sciences > Biochemical Phenomena, Metabolism, and Nutrition > Biochemical Phenomena > Nucleic Acid Denaturation Terms and Definitions

Nucleic Acid Denaturation

Medical Definition:	Disorganization of secondary structures of nucleic acids through cleavage of hydrogen bonds and hydrophobic linkages. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.
Guide Notes:	IM general only; coord NIM with DNA or RNA or specific (IM)

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