Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Azoles > Triazoles Terms and Definitions

Triazoles

Medical Definition:
Guide Notes:	includes triazolines, triazolidines

Triazoles Categories.

	Amitrole - A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
	Fluconazole - Triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.
	Guanazole - A cytostatic triazole derivative which is not to be confused with guanazolo, the generic name for 8-azaguanine.
	Itraconazole - One of the triazole ANTIFUNGAL AGENTS that inhibits cytochrome P-450-dependent enzymes resulting in impairment of ERGOSTEROL synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis & aspergillosis.
	Trapidil - A coronary vasodilator agent.

Triazoles Medical Definitions and Terms

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