Canadian Medical Guide > Chemicals and Drugs > Immunologic and Biological Factors > Immunologic Factors > Antigens > Autoantigens Terms and Definitions
Autoantigens
Medical Definition: | Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response. |
Previously Indexed: | Antigens (1966-1972) |
Heymann Nephritis Antigenic Complex - A complex of antigenic proteins obtained from the brush border of kidney tubules. It contains two principal components LDL-RECEPTOR RELATED PROTEIN 2 and LDL-RECEPTOR RELATED PROTEIN-ASSOCIATED PROTEIN. The name of this complex is derived from researcher, Dr. Walter Heymann, who developed an experimental model of membranous glomerulonephritis (GLOMERULONEPHRITIS) by injecting this antigenic complex into rats to induce an autoimmune response. |
Autoantigens Medical Definitions and Terms
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