Canadian Medical Guide > Chemicals and Drugs > Immunologic and Biological Factors > Immunologic Factors > Antibodies > Immunoglobulin Idiotypes Terms and Definitions
Immunoglobulin Idiotypes
Medical Definition: | Unique, genetically controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains. |
Guide Notes: | DF: IG IDIOTYPES |
Previously Indexed: | Anti-Antibodies (1966-1969),Antibody Specificity (1970-1978),Antigenic Determinants (1970-1978),Binding Sites, Antibody (1973-1978) |
Immunoglobulin Idiotypes Medical Definitions and Terms
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