Canadian Medical Guide > Chemicals and Drugs > Immunologic and Biological Factors > Immunologic Factors > Antibodies > Antibodies, Blocking Terms and Definitions

Antibodies, Blocking

Medical Definition:	Antibodies that inhibit the reaction between antigen and other antibodies or sensitized T-lymphocytes (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IgE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by cytotoxic T-lymphocytes have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)
Guide Notes:	antibodies inhibiting reaction between antigen and other antibodies or sensitized T-lymphocytes: not for any antibody reaction to an antigen ( = ANTIBODIES or specific antibody); do not coord with ANTIBODY FORMATION for /biosyn
Also Called:	Enhancing Antibodies

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