Canadian Medical Guide > Chemicals and Drugs > Nucleic Acids, Nucleotides, and Nucleosides > Nucleic Acids > Nucleic Acid Heteroduplexes Terms and Definitions

Nucleic Acid Heteroduplexes

Medical Definition:	Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
Guide Notes:	coord with specific DNA or RNA or both (IM)
Also Called:	Heteroduplex DNA
Previously Indexed:	Base Sequence (1971-1979),DNA (1966-1979),Mutation (1966-1979),Nucleic Acid Hybridization (1971-1979),RNA (1966-1979),Recombination, Genetic (1968-1979),specific DNA (1966-1979),specific RNA (1966-1979)

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