Ubiquitins
| Medical Definition: |
A family of proteins that are structurally-related to Ubiquitin. Ubiquitins and ubiquitin-like proteins participate in diverse cellular functions, such as protein degradation and HEAT-SHOCK RESPONSE, by conjugation to other proteins. |
| Guide Notes: |
UBIQUITIN is available |
| Also Called: |
Ubiquitin-Like Proteins |
| Previously Indexed: |
Chromosomal Proteins, Non-Histone (1977-1984),Nucleoproteins (1966-1977),Peptides (1975-1980) |
Ubiquitins Categories.
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Small Ubiquitin-Related Modifier Proteins - A class of structurally related proteins of 12-20 kD in size. They covalently modify specific proteins in a manner analogous to UBIQUITIN. |
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Ubiquitin - A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These "ubiquitinated" proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell. |
Ubiquitins Medical Definitions and Terms
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