RNA Processing, Post-Transcriptional
| Medical Definition: |
Post-transcriptional biological modification of messenger, transfer, or ribosomal RNAs or their precursors. It includes cleavage, methylation, thiolation, isopentenylation, pseudouridine formation, conformational changes, and association with ribosomal protein. |
| Guide Notes: |
coord IM with specific RNA /metab (IM); DF: RNA PROC POST TRANSCRIPTIONAL |
| Previously Indexed: |
Nucleic Acid Precursors (1975-1982),RNA, Messenger (1966-1982),Transcription, Genetic (1973-1982) |
RNA Processing, Post-Transcriptional Categories.
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RNA 3' End Processing - The steps that generate the 3' ends of mature RNA molecules. For most mRNAs (RNA, MESSENGER), 3' end processing referred to as POLYADENYLATION includes the addition of POLY A. |
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RNA Editing - A process that changes the nucleotide sequence of mRNA from that of the DNA template encoding it. Some major classes of RNA editing are as follows: 1, the conversion of cytosine to uracil in mRNA; 2, the addition of variable number of guanines at pre-determined sites; and 3, the addition and deletion of uracils, templated by guide-RNAs (RNA, GUIDE). |
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RNA Splicing - The ultimate exclusion of nonsense sequences or intervening sequences (introns) before the final RNA transcript is sent to the cytoplasm. |
RNA Processing, Post-Transcriptional Medical Definitions and Terms
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