Mixed Connective Tissue Disease
| Medical Definition: |
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence. |
| Guide Notes: |
disease entity: read definition & do not confuse with CONNECTIVE TISSUE DISEASES; DF: MCTD |
| Previously Indexed: |
Collagen Diseases (1972-1978),Lupus Erythematosus, Systemic (1972-1978),Scleroderma, Systemic (1972-1978) |
Mixed Connective Tissue Disease Medical Definitions and Terms
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