Subcellular Fractions
| Medical Definition: |
Components of a cell produced by various separation techniques which, though they disrupt the delicate anatomy of a cell, preserve the structure and physiology of its functioning constituents for biochemical and ultrastructural analysis. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p163) |
| Guide Notes: |
NIM; A 11 qualif except /cytol |
| Previously Indexed: |
Cytology (1966-1971),Microsomes (1966-1971) |
Subcellular Fractions Categories.
 |
Cell-Free System - A fractionated cell extract that maintains a biological function. A subcellular fraction isolated by ultracentrifugation or other separation techniques must first be isolated so that a process can be studied free from all of the complex side reactions that occur in a cell. The cell-free system is therefore widely used in cell biology. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p166) |
|
Microsomes - Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (Glick, Glossary of Biochemistry and Molecular Biology, 1990; from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed) |
|
Synaptosomes - Pinched-off nerve endings and their contents of vesicles and cytoplasm together with the attached subsynaptic area of the membrane of the post-synaptic cell. They are largely artificial structures produced by fractionation after selective centrifugation of nervous tissue homogenates. |
Subcellular Fractions Medical Definitions and Terms
|
|
|
 |
 |
 CANADIAN
MEDICAL GUIDE
|
| Thank you for visiting
Canadian Medical Guide .com | | | | | |
|
|
 |
   |
 |
Canadian Medical Guide Catagories
| | |
