Inclusion Bodies
| Medical Definition: |
A generic term for any circumscribed mass of foreign (e.g., lead or viruses) or metabolically inactive materials (e.g., ceroid or Mallory bodies), within the cytoplasm or nucleus of a cell. Inclusion bodies are in cells infected with certain filtrable viruses, observed especially in nerve, epithelial, or endothelial cells. (Stedman, 25th ed) |
| Guide Notes: |
A 11 qualif except /cytol; /genet permitted; for bacteria, coord IM with specific bacterium (IM); for viruses, INCLUSION BODIES, VIRAL is available: see note there |
| Also Called: |
Cytoplasmic Inclusions |
| Previously Indexed: |
Cytoplasmic Granules (1966-1969) |
Inclusion Bodies Categories.
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Inclusion Bodies, Viral - An area showing altered staining behavior in the nucleus or cytoplasm of a virus-infected cell. Some inclusion bodies represent "virus factories" in which viral nucleic acid or protein is being synthesized; others are merely artifacts of fixation and staining. One example, Negri bodies, are found in the cytoplasm or processes of nerve cells in animals that have died from rabies. |
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Intranuclear Inclusion Bodies - Circumscribed masses of foreign or metabolically inactive materials, within the CELL NUCLEUS. Some are VIRAL INCLUSION BODIES. |
Inclusion Bodies Medical Definitions and Terms
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