Animals, Inbred Strains
| Medical Definition: |
Animals produced by the mating of littermates or siblings over multiple generations. The resultant strain of animals is virtually identical genotypically. Highly inbred animal lines allow the study of certain traits in a relatively pure form. (Segen, Dictionary of Modern Medicine, 1992) |
| Guide Notes: |
IM GEN or unspecified; coord NIM with specific exper animal (NIM); when IM, qualif permitted; do not forget also to check tag ANIMALS |
| Previously Indexed: |
Inbreeding (1970-1993) |
Animals, Inbred Strains Categories.
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Animals, Congenic - Inbred strains of animals that are genetically identical except at a single locus, or a few specified loci, so that their known genetic differences are expressed in the same genetic background. A congenic strain is produced by outbreeding a strain and then eliminating the background by many generations of backcrosses while maintaining the desired genetic differences by selection of progeny. (Dorland, 28th ed) |
Animals, Inbred Strains Medical Definitions and Terms
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