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Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Alkaloids > Camptothecin Terms and Definitions

Camptothecin

Medical Definition: An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
CAS Type 1 Name: CAS Number: 7689-03-4
Previously Indexed: Alkaloids (1966-1972),Antineoplastic Agents (1966-1972)
Camptothecin Categories.
Canadian Medical Guide Definition Topotecan - An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.

Camptothecin Medical Definitions and Terms

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